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Potential of afatinib in the treatment of patients with HER2-positive breast cancer

In the absence of treatment, overexpression of the human epidermal growth factor receptor 2 (HER2) predicts a poor prognosis in breast cancer. In the last decade, monoclonal antibodies and small molecule tyrosine kinase inhibitors have significantly improved the outcome of HER2-positive breast cance...

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Bibliografiske detaljer
Main Authors: Geuna, Elena, Montemurro, Filippo, Aglietta, Massimo, Valabrega, Giorgio
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846413/
https://ncbi.nlm.nih.gov/pubmed/24367201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S25868
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