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Role of trastuzumab in the management of HER2-positive metastatic breast cancer

Breast cancer is a major health issue in developed countries. Overexpression of HER2, a member of epidermal growth factor receptor family, occurs in 20%–30% of breast cancers. HER2 drives the cancer cells to develop a more aggressive phenotype, to metastasize to viscera and central nervous system, a...

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Hlavní autoři: Milani, Andrea, Montemurro, Filippo, Gioeni, Luisa, Aglietta, Massimo, Valabrega, Giorgio
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846373/
https://ncbi.nlm.nih.gov/pubmed/24367170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S6070
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