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Role of trastuzumab in the management of HER2-positive metastatic breast cancer
Breast cancer is a major health issue in developed countries. Overexpression of HER2, a member of epidermal growth factor receptor family, occurs in 20%–30% of breast cancers. HER2 drives the cancer cells to develop a more aggressive phenotype, to metastasize to viscera and central nervous system, a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846373/ https://ncbi.nlm.nih.gov/pubmed/24367170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S6070 |
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