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Potential of afatinib in the treatment of patients with HER2-positive breast cancer
In the absence of treatment, overexpression of the human epidermal growth factor receptor 2 (HER2) predicts a poor prognosis in breast cancer. In the last decade, monoclonal antibodies and small molecule tyrosine kinase inhibitors have significantly improved the outcome of HER2-positive breast cance...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846413/ https://ncbi.nlm.nih.gov/pubmed/24367201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S25868 |
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