A Functional Mouse Retroposed Gene Fg01 Reduces Alzheimer’s β-Amyloid Levels and Tau Phosphorylation

Senile plaques consisting of β-amyloid (Aβ) and neurofibrillary tangles composed of hyperphosphorylated tau are major pathological hallmarks of Alzheimer’s disease (AD). Elucidation of factors that modulate Aβ generation and tau hyperphosphorylation is crucial for AD intervention. Here we identify a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Yun-wu, Liu, Shijie, Zhang, Xue, Li, Wu-Bo, Chen, Yaomin, Huang, Xiumei, Sun, Liangwu, Luo, Wenjie, Netzer, William J., Threadgill, Richard, Wiegand, Gordon, Wang, Ruishan, Cohen, Stanley N., Greengard, Paul, Liao, Francesca-Fang, Li, Limin, Xu, Huaxi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846276/
https://ncbi.nlm.nih.gov/pubmed/19914182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.08.036
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados