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A Functional Mouse Retroposed Gene Fg01 Reduces Alzheimer’s β-Amyloid Levels and Tau Phosphorylation
Senile plaques consisting of β-amyloid (Aβ) and neurofibrillary tangles composed of hyperphosphorylated tau are major pathological hallmarks of Alzheimer’s disease (AD). Elucidation of factors that modulate Aβ generation and tau hyperphosphorylation is crucial for AD intervention. Here we identify a...
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| Glavni autori: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846276/ https://ncbi.nlm.nih.gov/pubmed/19914182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.08.036 |
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