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Chaperones increase association of tau protein with microtubules

Molecular chaperones and their functions in protein folding have been implicated in several neurodegenerative diseases, including Parkinson's disease and Huntington's disease, which are characterized by accumulation of protein aggregates (e.g., α-synuclein and huntingtin, respectively). Th...

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Detalhes bibliográficos
Main Authors: Dou, Fei, Netzer, William J., Tanemura, Kentaro, Li, Feng, Hartl, F. Ulrich, Takashima, Akihiko, Gouras, Gunnar K., Greengard, Paul, Xu, Huaxi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141063/
https://ncbi.nlm.nih.gov/pubmed/12522269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242720499
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