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Chaperones increase association of tau protein with microtubules

Molecular chaperones and their functions in protein folding have been implicated in several neurodegenerative diseases, including Parkinson's disease and Huntington's disease, which are characterized by accumulation of protein aggregates (e.g., α-synuclein and huntingtin, respectively). Th...

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Bibliografiske detaljer
Main Authors: Dou, Fei, Netzer, William J., Tanemura, Kentaro, Li, Feng, Hartl, F. Ulrich, Takashima, Akihiko, Gouras, Gunnar K., Greengard, Paul, Xu, Huaxi
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141063/
https://ncbi.nlm.nih.gov/pubmed/12522269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242720499
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