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Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence
During retinal development, photoreceptors and bipolar cells express the transcription factor Otx2. Blimp1 is transiently expressed in Otx2+ cells. Blimp1 deletion results in excess bipolar cell formation at the expense of photoreceptors. In principle, Blimp1 could be expressed only in Otx2+ cells t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845674/ https://ncbi.nlm.nih.gov/pubmed/24125957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.10.006 |
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