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Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein-E knockout mice

BACKGROUND: All three isoforms of the nitric oxide synthase (NOS) are expressed in the atherosclerotic plaque. To test whether neuronal NOS (nNOS) deficiency affects atherosclerosis, we studied “western-type” diet fed apoE/nNOSα double knockout (DKO) mice, which carry a deletion of nNOS exon 2 and a...

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Detalhes bibliográficos
Main Authors: Kuhlencordt, Peter J., Hötten, Stefanie, Schödel, Johannes, Rützel, Sebastian, Hu, Kai, Widder, Julian, Marx, Alexander, Huang, Paul L., Ertl, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845660/
https://ncbi.nlm.nih.gov/pubmed/16627802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000223143.88128.19
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