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Oxidative Stress and Compartment of Gene Expression Determine Proatherosclerotic Effects of Inducible Nitric Oxide Synthase

Genetic and pharmacological inhibition of inducible nitric oxide synthase (iNOS) decreases atherosclerosis development. Potential proatherogenic effects of iNOS include iNOS mediated oxidative stress and iNOS expression in different cellular compartments. Lesional iNOS can potentially produce nitric...

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Hlavní autoři: Ponnuswamy, Padmapriya, Ostermeier, Eva, Schröttle, Angelika, Chen, Jiqiu, Huang, Paul L., Ertl, Georg, Nieswandt, Bernhard, Kuhlencordt, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684203/
https://ncbi.nlm.nih.gov/pubmed/19465644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080730
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