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An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family

Recurrent viral pressure has acted on host-encoded antiviral genes during primate and mammalian evolution. This selective pressure has resulted in dramatic episodes of adaptation in host antiviral genes, often detected via positive selection. These evolutionary signatures of adaptation have the pote...

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Detalhes bibliográficos
Main Authors: Malfavon-Borja, Ray, Sawyer, Sara L., Wu, Lily I., Emerman, Michael, Malik, Harmit S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845644/
https://ncbi.nlm.nih.gov/pubmed/24158625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evt163
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