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Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes
TRIM5 is a host antiviral gene with an evolutionary history of genetic conflict with retroviruses. The TRIMCyp gene encodes a protein fusion of TRIM5 effector domains with the capsid-binding ability of a retrotransposed CyclophilinA (CypA), resulting in novel antiviral specificity against lentivirus...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574956/ https://ncbi.nlm.nih.gov/pubmed/23319649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216542110 |
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