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IGF-1R as an anti-cancer target—trials and tribulations

Type I insulin-like growth factor receptor (IGF-1R) has long been recognized for its role in tumorigenesis and growth, but only recently have the tools for targeting the IGF pathway become available. More than 10 IGF/IGF-1R inhibitors have entered clinical trials, and these belong to three main clas...

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Detalhes bibliográficos
Main Authors: Chen, Helen X., Sharon, Elad
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845553/
https://ncbi.nlm.nih.gov/pubmed/23601239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10263
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