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Impact of genetic alterations on mTOR-targeted cancer therapy

Rapamycin and its derivatives (rapalogs), a group of allosteric inhibitors of mammalian target of rapamycin (mTOR), have been actively tested in a variety of cancer clinical trials, and some have been approved by the Food and Drug Administration for the treatment of certain types of cancers. However...

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Detalhes bibliográficos
Autor principal: Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845552/
https://ncbi.nlm.nih.gov/pubmed/23489586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.013.10005
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