Mechanism of chiral proofreading during translation of the genetic code

The biological macromolecular world is homochiral and effective enforcement and perpetuation of this homochirality is essential for cell survival. In this study, we present the mechanistic basis of a configuration-specific enzyme that selectively removes D-amino acids erroneously coupled to tRNAs. T...

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Detalhes bibliográficos
Main Authors: Ahmad, Sadeem, Routh, Satya Brata, Kamarthapu, Venu, Chalissery, Jisha, Muthukumar, Sowndarya, Hussain, Tanweer, Kruparani, Shobha P, Deshmukh, Mandar V, Sankaranarayanan, Rajan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845328/
https://ncbi.nlm.nih.gov/pubmed/24302572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01519
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