Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins

Matrix mechanics controls cell fate by modulating the bonds between integrins and extracellular matrix (ECM) proteins. However, it remains unclear how fibronectin (FN), type 1 collagen, and their receptor integrin subtypes distinctly control force transmission to regulate focal adhesion kinase (FAK)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Seong, Jihye, Tajik, Arash, Sun, Jie, Guan, Jun-Lin, Humphries, Martin J., Craig, Susan E., Shekaran, Asha, García, Andrés J., Lu, Shaoying, Lin, Michael Z., Wang, Ning, Wang, Yingxiao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845171/
https://ncbi.nlm.nih.gov/pubmed/24222685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307405110
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