Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins

Matrix mechanics controls cell fate by modulating the bonds between integrins and extracellular matrix (ECM) proteins. However, it remains unclear how fibronectin (FN), type 1 collagen, and their receptor integrin subtypes distinctly control force transmission to regulate focal adhesion kinase (FAK)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Seong, Jihye, Tajik, Arash, Sun, Jie, Guan, Jun-Lin, Humphries, Martin J., Craig, Susan E., Shekaran, Asha, García, Andrés J., Lu, Shaoying, Lin, Michael Z., Wang, Ning, Wang, Yingxiao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2013
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845171/
https://ncbi.nlm.nih.gov/pubmed/24222685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307405110
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