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Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins
Matrix mechanics controls cell fate by modulating the bonds between integrins and extracellular matrix (ECM) proteins. However, it remains unclear how fibronectin (FN), type 1 collagen, and their receptor integrin subtypes distinctly control force transmission to regulate focal adhesion kinase (FAK)...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845171/ https://ncbi.nlm.nih.gov/pubmed/24222685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307405110 |
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