Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins

Matrix mechanics controls cell fate by modulating the bonds between integrins and extracellular matrix (ECM) proteins. However, it remains unclear how fibronectin (FN), type 1 collagen, and their receptor integrin subtypes distinctly control force transmission to regulate focal adhesion kinase (FAK)...

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Bibliografische gegevens
Hoofdauteurs: Seong, Jihye, Tajik, Arash, Sun, Jie, Guan, Jun-Lin, Humphries, Martin J., Craig, Susan E., Shekaran, Asha, García, Andrés J., Lu, Shaoying, Lin, Michael Z., Wang, Ning, Wang, Yingxiao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
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Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845171/
https://ncbi.nlm.nih.gov/pubmed/24222685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307405110
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