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Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response
L-type Ca(2+) currents conducted by Ca(V)1.2 channels initiate excitation–contraction coupling in the heart. Their activity is increased by β-adrenergic/cAMP signaling via phosphorylation by PKA in the fight-or-flight response, but the sites of regulation are unknown. We describe the functional role...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845157/ https://ncbi.nlm.nih.gov/pubmed/24218620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319421110 |
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