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BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease

Bone morphogenetic protein 9 (BMP9) promotes the acquisition of the cholinergic phenotype in basal forebrain cholinergic neurons (BFCN) during development and protects these neurons from cholinergic dedifferentiation following axotomy when administered in vivo. A decline in BFCN function occurs in p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Burke, Rebecca M., Norman, Timothy A., Haydar, Tarik F., Slack, Barbara E., Leeman, Susan E., Blusztajn, Jan Krzysztof, Mellott, Tiffany J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845152/
https://ncbi.nlm.nih.gov/pubmed/24218590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319297110
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