BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease

Bone morphogenetic protein 9 (BMP9) promotes the acquisition of the cholinergic phenotype in basal forebrain cholinergic neurons (BFCN) during development and protects these neurons from cholinergic dedifferentiation following axotomy when administered in vivo. A decline in BFCN function occurs in p...

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Detalhes bibliográficos
Main Authors: Burke, Rebecca M., Norman, Timothy A., Haydar, Tarik F., Slack, Barbara E., Leeman, Susan E., Blusztajn, Jan Krzysztof, Mellott, Tiffany J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845152/
https://ncbi.nlm.nih.gov/pubmed/24218590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319297110
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