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Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins
The rapidly growing recognition of the role of oncogenic ROS1 fusion proteins in the malignant transformation of multiple cancers, including lung adenocarcinoma, cholangiocarcinoma, and glioblastoma, is driving efforts to develop effective ROS1 inhibitors for use as molecularly targeted therapy. Usi...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845150/ https://ncbi.nlm.nih.gov/pubmed/24218589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319583110 |
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