Overexpression of Twinkle-helicase protects cardiomyocytes from genotoxic stress caused by reactive oxygen species

Lignende værker

• Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes
  af: Wanrooij, Sjoerd, et al.
  Udgivet: (2007)
• Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling
  af: Goffart, Steffi, et al.
  Udgivet: (2009)
• Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
  af: Pohjoismäki, Jaakko L. O., et al.
  Udgivet: (2012)
• The Overexpression of Twinkle Helicase Ameliorates the Progression of Cardiac Fibrosis and Heart Failure in Pressure Overload Model in Mice
  af: Tanaka, Atsushi, et al.
  Udgivet: (2013)
• Twist and Turn—Topoisomerase Functions in Mitochondrial DNA Maintenance
  af: Goffart, Steffi, et al.
  Udgivet: (2019)