Fibroblasts from methotrexate-sensitive mice accumulate methotrexate polyglutamates but those from methotrexate-resistant mice do not

OBJECTIVE: We and others have previously demonstrated that methotrexate (MTX) mediates its anti-inflammatory effects through increase in cellular release of adenosine. Consistent with this observation, there is no increase in adenosine from exudates of mouse strains resistant to MTX. Because intrace...

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Detaylı Bibliyografya
Asıl Yazarlar: You, Xin, Williams, Adrienne, Dervieux, Thierry, He, Wenjie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844927/
https://ncbi.nlm.nih.gov/pubmed/23464989
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