BRI2 Inhibits Amyloid β-Peptide Precursor Protein Processing by Interfering with the Docking of Secretases to the Substrate

Lignende værker

• BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2
  af: Matsuda, Shuji, et al.
  Udgivet: (2009)
• APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant
  af: Tamayev, Robert, et al.
  Udgivet: (2011)
• Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles
  af: Matsuda, Shuji, et al.
  Udgivet: (2009)
• β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia
  af: Tamayev, Robert, et al.
  Udgivet: (2012)
• The Intracellular Threonine of Amyloid Precursor Protein That Is Essential for Docking of Pin1 Is Dispensable for Developmental Function
  af: Barbagallo, Alessia P. M., et al.
  Udgivet: (2011)