Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

Distinguishing the primary from secondary effects and compensatory mechanisms is of crucial importance in understanding adult-onset neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). Transgenic mice that overexpress the G93A mutation of the human Cu-Zn superoxide dismutase 1 gen...

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Autors principals: van Zundert, Brigitte, Peuscher, Marieke H., Hynynen, Meri, Chen, Adam, Neve, Rachael L., Brown, Robert H., Constantine-Paton, Martha, Bellingham, Mark C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844745/
https://ncbi.nlm.nih.gov/pubmed/18945894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1340-08.2008
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