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Early Pathogenesis in the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by dysfunction and degeneration of motor neurons starting in adulthood. Most of our knowledge about the pathophysiological mechanisms of ALS comes from transgenic mice models that emulate a subgroup of familial ALS cases...

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Detalhes bibliográficos
Main Authors: van Zundert, Brigitte, Izaurieta, Pamela, Fritz, Elsa, Alvarez, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886915/
https://ncbi.nlm.nih.gov/pubmed/22740507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24234
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