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Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to Lead (Pb)

Late Onset Alzheimer Disease (LOAD) constitutes the majority of AD cases (~90%). Amyloidosis and tau pathology, which are present in AD brains, appear to be sporadic in nature. We have previously shown that infantile lead (Pb) exposure is associated with a change in the expression and regulation of...

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Hlavní autoři: Bihaqi, Syed Waseem, Zawia, Nasser H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844042/
https://ncbi.nlm.nih.gov/pubmed/23973560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.07.010
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