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In vitro Pb exposure disturbs the balance between Aβ production and elimination: the role of AβPP and Neprilysin
Metabolism of β-amyloid peptide (Aβ) is closely associated with the pathology and etiology of Alzheimer’s disease (AD). Our previous studies on aging primates and rodents have revealed that early life lead exposure increases the expression of the β-amyloid precursor protein (AβPP), elevates Aβ level...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086455/ https://ncbi.nlm.nih.gov/pubmed/21315759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.02.001 |
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