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Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease

INTRODUCTION: Early life lead (Pb) exposure results in a latent increase in Alzheimer's disease (AD)–related proteins, and cognitive deficits late in life in both rodents and primates. This study was conducted to investigate if these late life changes were accompanied by epigenetic alterations....

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Eid, Aseel, Bihaqi, Syed Waseem, Renehan, William E., Zawia, Nasser H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879653/
https://ncbi.nlm.nih.gov/pubmed/27239543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.02.002
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