Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.

The long-term efficacy of gene therapy using bone marrow transplantation requires the engraftment of genetically altered totipotent hematopoietic stem cells (THSCs). Ex vivo expansion of corrected THSCs is one way to increase the efficiency of the procedure. Similarly, selective in vivo expansion of...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Kirby, S L, Cook, D N, Walton, W, Smithies, O
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9402
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