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Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.

The long-term efficacy of gene therapy using bone marrow transplantation requires the engraftment of genetically altered totipotent hematopoietic stem cells (THSCs). Ex vivo expansion of corrected THSCs is one way to increase the efficiency of the procedure. Similarly, selective in vivo expansion of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kirby, S L, Cook, D N, Walton, W, Smithies, O
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38440/
https://ncbi.nlm.nih.gov/pubmed/8790342
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