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Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.

The long-term efficacy of gene therapy using bone marrow transplantation requires the engraftment of genetically altered totipotent hematopoietic stem cells (THSCs). Ex vivo expansion of corrected THSCs is one way to increase the efficiency of the procedure. Similarly, selective in vivo expansion of...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Kirby, S L, Cook, D N, Walton, W, Smithies, O
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9402
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