Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein

OBJECTIVES: Proteinase-activated receptors (PARs) -1 and -2 have been associated with increased invasiveness and metastasis in human malignancies. The role of PAR-3 has been less investigated. We examined the role of PARs in a human pancreatic adenocarcinoma PANC-1 cell line phenotype in vitro. METH...

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Hauptverfasser: Segal, Liora, Katz, Liora S., Lupu-Meiri, Monica, Shapira, Hagit, Sandbank, Judith, Gershengorn, Marvin C., Oron, Yoram
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843996/
https://ncbi.nlm.nih.gov/pubmed/23921961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e31829f0b81
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