Knock-down of plasminogen-activator inhibitor-1 enhances expression of E-cadherin and promotes epithelial differentiation of human pancreatic adenocarcinoma cells

High levels of plasminogen activator inhibitor-1 (PAI-1), which is produced by stromal, endothelial and cancer cells and has multiple complex effects on cancers, correlate with poor cancer prognosis. To more definitively study the role of endogenously produced PAI-1 in human pancreatic adenocarcinom...

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Bibliografische gegevens
Hoofdauteurs: Lupu-Meiri, Monica, Geras-Raaka, Elizabeth, Lupu, Ruth, Shapira, Hagit, Sandbank, Judith, Segal, Liora, Gershengorn, Marvin C., Oron, Yoram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469200/
https://ncbi.nlm.nih.gov/pubmed/22331587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24068
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