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Knock-down of plasminogen-activator inhibitor-1 enhances expression of E-cadherin and promotes epithelial differentiation of human pancreatic adenocarcinoma cells

High levels of plasminogen activator inhibitor-1 (PAI-1), which is produced by stromal, endothelial and cancer cells and has multiple complex effects on cancers, correlate with poor cancer prognosis. To more definitively study the role of endogenously produced PAI-1 in human pancreatic adenocarcinom...

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Detalhes bibliográficos
Main Authors: Lupu-Meiri, Monica, Geras-Raaka, Elizabeth, Lupu, Ruth, Shapira, Hagit, Sandbank, Judith, Segal, Liora, Gershengorn, Marvin C., Oron, Yoram
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469200/
https://ncbi.nlm.nih.gov/pubmed/22331587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24068
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