Wordt geladen...

Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase C

1. C335Stop is a constitutively active mutant of the TRH receptor (TRH-R). To investigate the mechanism of the decreased responsiveness of C335Stop TRH-R, we studied cellular Ca(2+) concentrations ([Ca(2+)](i)) in AtT20 cells stably transfected with C335Stop TRH-R cDNA, or Ca(2+)-activated chloride...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Grimberg, Hagit, Zaltsman, Ilona, Lupu-Meiri, Monica, Gershengorn, Marvin C, Oron, Yoram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565886/
https://ncbi.nlm.nih.gov/pubmed/10204996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702415
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!