Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis

Histone deacetylases (HDAC) are present in the epidermal layer of the skin, outer root sheath and hair matrix. To investigate how histone acetylation affects skin morphogenesis and homeostasis, mice were generated with a K14 promoter-mediated reduction of Hdac1 or Hdac2. The skin of HDAC1 null (K14-...

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Detalhes bibliográficos
Main Authors: Hughes, Michael W., Jiang, Ting-Xin, Lin, Sung-Jan, Leung, Yvonne, Kobielak, Krzysztof, Widelitz, Randall B., Chuong, Cheng Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843967/
https://ncbi.nlm.nih.gov/pubmed/23792463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.283
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