Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis

Histone deacetylases (HDAC) are present in the epidermal layer of the skin, outer root sheath and hair matrix. To investigate how histone acetylation affects skin morphogenesis and homeostasis, mice were generated with a K14 promoter-mediated reduction of Hdac1 or Hdac2. The skin of HDAC1 null (K14-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hughes, Michael W., Jiang, Ting-Xin, Lin, Sung-Jan, Leung, Yvonne, Kobielak, Krzysztof, Widelitz, Randall B., Chuong, Cheng Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843967/
https://ncbi.nlm.nih.gov/pubmed/23792463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.283
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