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HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

Colorectal carcinoma RKO cells expressing reduced levels of the RNA-binding protein HuR (ASHuR) displayed markedly reduced growth. In synchronous RKO populations, HuR was almost exclusively nuclear during early G(1), increasing in the cytoplasm during late G(1), S and G(2). The expression and half-l...

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Detalhes bibliográficos
Main Authors: Wang, Wengong, Caldwell, M.Craig, Lin, Shankung, Furneaux, Henry, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384372/
https://ncbi.nlm.nih.gov/pubmed/10811625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.10.2340
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