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Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins

Calcitonin gene-related peptide (CGRP) and adrenomedullin (AM) are related peptides that are potent vasodilators. The CGRP and AM receptors are heteromeric protein complexes comprised of a shared calcitonin receptor-like receptor (CLR) subunit and a variable receptor activity modifying protein (RAMP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moad, Heather E, Pioszak, Augen A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843631/
https://ncbi.nlm.nih.gov/pubmed/24115156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2377
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