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Bacterial expression and purification of a heterodimeric Adrenomedullin receptor extracellular domain complex using DsbC-assisted disulfide shuffling

Adrenomedullin (AM) is a peptide hormone that is a potent vasodilator and is essential for vascular development. The AM receptor is a heterodimeric cell surface receptor composed of the calcitonin receptor-like receptor (CLR), a class B G protein-coupled receptor, in association with either of two r...

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Detalhes bibliográficos
Main Authors: Hill, Heather E., Pioszak, Augen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568255/
https://ncbi.nlm.nih.gov/pubmed/23247088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.11.019
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