µ1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors
The heterotetrameric AP-1 complex is involved in the formation of clathrin-coated vesicles at the trans-Golgi network (TGN) and interacts with sorting signals in the cytoplasmic tails of cargo molecules. Targeted disruption of the mouse µ1A-adaptin gene causes embryonic lethality at day 13.5. In cel...
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| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.10.2193 |
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