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Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

Pax5 (BSAP) functions as both a transcriptional activator and repressor during midbrain patterning, B-cell development and lymphomagenesis. Here we demonstrate that Pax5 exerts its repression function by recruiting members of the Groucho corepressor family. In a yeast two-hybrid screen, the groucho-...

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Detalhes bibliográficos
Main Authors: Eberhard, Dirk, Jiménez, Gerardo, Heavey, Barry, Busslinger, Meinrad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384353/
https://ncbi.nlm.nih.gov/pubmed/10811620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.10.2292
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