Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family
Pax5 (BSAP) functions as both a transcriptional activator and repressor during midbrain patterning, B-cell development and lymphomagenesis. Here we demonstrate that Pax5 exerts its repression function by recruiting members of the Groucho corepressor family. In a yeast two-hybrid screen, the groucho-...
Sparad:
| I publikationen: | EMBO J |
|---|---|
| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Nature Publishing Group
2000
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.10.2292 |
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