Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

Pax5 (BSAP) functions as both a transcriptional activator and repressor during midbrain patterning, B-cell development and lymphomagenesis. Here we demonstrate that Pax5 exerts its repression function by recruiting members of the Groucho corepressor family. In a yeast two-hybrid screen, the groucho-...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Eberhard, Dirk, Jiménez, Gerardo, Heavey, Barry, Busslinger, Meinrad
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2000
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.10.2292
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