Wird geladen...
Protective roles for caspase-8 and cFLIP in adult homeostasis
Caspase-8 or cFLIP deficiency leads to embryonic lethality in mice due to defects in endothelial tissues. Caspase-8(−/−), RIPK3(−/−), but not cFLIP(−/−), RIPK3(−/−), double-knockout animals develop normally, indicating that caspase-8 antagonizes the lethal effects of RIPK3 during development. Here w...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843376/ https://ncbi.nlm.nih.gov/pubmed/24095739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.045 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|