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Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis.

DL-alpha-Difluoromethylornithine, a polyamine biosynthesis inhibitor, and bleomycin, a currently used antineoplastic agent, have each previously been shown to be curative for acute short-term infections of mice with Trypanosoma brucei brucei, an African trypanosome closely related to those that caus...

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Hlavní autoři: Clarkson, A B, Bacchi, C J, Mellow, G H, Nathan, H C, McCann, P P, Sjoerdsma, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384332/
https://ncbi.nlm.nih.gov/pubmed/6193522
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