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Direct evidence for interaction between human erythroid progenitor cells and a hemoglobin switching activity present in fetal sheep serum.

An activity that induces Hb F to Hb A switching in human cells is present in fetal sheep serum. To test directly the role of cell-to-environment interactions in hemoglobin switching and to define the level of erythroid cell differentiation at which this activity operates, colony transfer experiments...

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Dettagli Bibliografici
Autori principali: Stamatoyannopoulos, G, Nakamoto, B, Kurachi, S, Papayannopoulou, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1983
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC384316/
https://ncbi.nlm.nih.gov/pubmed/6193519
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