Llwytho...

The modulation of Hb F synthesis in adult erythroid progenitor (burst-forming unit) cultures reflects changes in gamma-globin gene transcription and chromatin structure.

Fetal hemoglobin production can be reactivated in vivo in adult persons with various hemoglobinopathies and other hemopoietic disorders, and in cultures of adult erythroid progenitors. We show that the activation of Hb F in adult cells is transcriptional in nature and is accompanied by the appearanc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Groudine, M, Peretz, M, Nakamoto, B, Papayannopoulou, T, Stamatoyannopoulos, G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1986
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC386615/
https://ncbi.nlm.nih.gov/pubmed/2428043
Tagiau: Ychwanegu Tag
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