Deficiency of a Glycogen Synthase-associated Protein, Epm2aip1, Causes Decreased Glycogen Synthesis and Hepatic Insulin Resistance

Glycogen synthesis is a major component of the insulin response, and defective glycogen synthesis is a major portion of insulin resistance. Insulin regulates glycogen synthase (GS) through incompletely defined pathways that activate the enzyme through dephosphorylation and, more potently, allosteric...

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Päätekijät: Turnbull, Julie, Tiberia, Erica, Pereira, Sandra, Zhao, Xiaochu, Pencea, Nela, Wheeler, Anne L., Yu, Wen Qin, Ivovic, Alexander, Naranian, Taline, Israelian, Nyrie, Draginov, Arman, Piliguian, Mark, Frankland, Paul W., Wang, Peixiang, Ackerley, Cameron A., Giacca, Adria, Minassian, Berge A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843075/
https://ncbi.nlm.nih.gov/pubmed/24142699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.483198
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