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Inhibiting Glycogen Synthesis Prevents Lafora Disease in a Mouse Model
Lafora disease (LD) is a fatal progressive myoclonus epilepsy characterized neuropathologically by aggregates of abnormally structured glycogen and proteins (Lafora bodies, LB), and neurodegeneration. Whether LB could be prevented by inhibiting glycogen synthesis and whether they are pathogenic rema...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823666/ https://ncbi.nlm.nih.gov/pubmed/23913475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23899 |
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